We are looking for a Master student with background in molecular biology and/or biochemistry and an interest in plant biology.

O-GlcNAcylation is a common post-translational modification of nuclear and cytoplasmic proteins, where a single N-acetyl-glucosamine (GlcNAc) molecule is attached to serine or threonine residues of a wide range of different proteins. The modification can affect protein interactions as well as sub-cellular localisation or stability of target proteins. O-GlcNAcylation is intensely studied in animal systems, but very little is known about this protein modification in plants, and few O-GlcNAcylated plant proteins have been identified so far.

We have previoulsy identified proteins that interact with plant O-GlcNAc Transferases (OGTs). In this master project, putative OGT-interacting proteins will be studied. The work will include cloning and transient expression of these interactors, as well as protein-protein interaction- and O-GlcNAcylation assays.

Duration: 6 months, funded by an FWF-project

If you are interested, please contact doris.lucyshyn@boku.ac.at

Doris Lucyshyn

Department of Applied Genetics and Cell Biology,

BOKU - University of Natural Resources and Life Sciences Vienna,

Austria