Infection of wounds constitutes a global problem and is furthermore one of the most common reasons for the non-healing of wounds. Especially medical facilities struggle with the consequences of postoperative wound infections. Current methods for its detection are based on simple wound status evaluation, PCR or cultivation that makes a timely evaluation of the wound’s contamination level hardly possible.
Novel diagnostic tools based on enzyme responsive materials could enable a fast and simple detection of wound infection. Thereby endogenous enzymes are detected that are released into the plasma and accumulate in the wound fluid.
Target of the thesis is the preparation of enzyme responsive materials as well as testing of these substrates on enzymes.

Methods
Chemical synthesis, analytics, enzymology

Prerequisite
University/FH students whose studies are related to chemistry, biotechnology or material science

Duration: min. 2 months (bachelor thesis)

Start: as of now

Place: BOKU, IFA Tulln, Konrad‐Lorenz‐Straße 20, 3430 Tulln
Institute for Environmental Biotechnology, Biomaterial and Enzyme Technology,
Prof. Gübitz

Contact: Gregor Tegl (gregor.tegl@boku.ac.at)