The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Type II system is currently the most commonly used RNA-Guided Endonuclease technology for genome engineering. Originally derived from bacteria, its use is now well established in a lot of different organisms. The diploma/master thesis will focus on the adaption and optimization of the CRISPR/Cas9 system for the generation of knockout strains and the introduction of other mutations into the genome of the yeast Pichia pastoris.

We are looking for a highly motivated and ambitious Diploma/Master Student who wants to join our group and work on this topic!

Start: January/February 2015

If you are interested please contact: Dr. Brigitte Gasse (brigitte.gasser@boku.ac.at) or Lina Heistinger (lina.heistinger@boku.ac.at)